Reference:

Mean Change From Baseline in CAARS*-Investigator Rated Total Score Total Score (n=394) 1
*CAARS=Conners' Adult ADHD Rating Scale.
†A 5-week, double-blind, randomized fixed-dose study in 401 adults with ADHD, aged 18-63 years, receiving CONCERTA^® 18, 36, 72 mg or placebo.
‡Compared to placebo.

Reference: 1. Medori R, Ramos-Quiroga JA, Casas M, et al. A randomized, placebo-controlled trial of three fixed dosages of prolonged-release OROS methylphenidate in adults with attention-deficit/hyperactivity disorder. Biol Psychiatry. 2008; 63: 981-989.

Reference: 2. Data on file, (CON025), Janssen-Cilag.